Protein binding of clindamycin in vivo by means of intravascular microdialysis in healthy volunteers.

Beatrix WulkersdorferSebastian G WichaElizaveta KurdinaStephan F Carrion CarreraPeter Matzneller Valentin Al JalaliMatthias G VossenSonja RiesenhuberEdith LacknerChristoph DornMarkus Zeitlinger

Published in: The Journal of antimicrobial chemotherapy (2021)

Concentration-dependent PB was observed for both investigated methods with slightly lower levels of unbound drug fractions in vitro as compared with in vivo.

Keyphrases

binding protein
heavy metals
coronary artery
protein protein
atomic force microscopy
adverse drug
amino acid
emergency department
dna binding
drug induced
risk assessment
aqueous solution
high resolution
electronic health record