Integrated Network Pharmacology and Experimental Validation Approach to Investigate the Mechanisms of Radix Rehmanniae Praeparata - Angelica Sinensis - Radix Achyranthis Bidentatae in Treating Knee Osteoarthritis.
Lang LiuBinghua ZhangZhenwei ZhouJie YangAilin LiYongji WuZeyu PengXiangyan LiZhonghua LiuXiangyang LengChangwei ZhaoHaisi DongWenhai ZhaoPublished in: Drug design, development and therapy (2024)
RAR inhibited extracellular matrix (ECM) degradation and oxidative stress response via the MAPK signaling pathway in KOA, and Mapk1 may be a core target.