Plasma calprotectin and new-onset type 2 diabetes in the general population: a prospective cohort study.
Arno R BourgonjeMartin F BourgonjeSara SokootiSacha La Bastide-Van GemertTom NilsenClara HiddenRon T GansevoortDouwe Johannes MulderJan-Luuk HillebrandsStephan J L BakkerAndré P van BeekRobin P F DullaartHarry Van GoorAmaal Eman AbdullePublished in: The Journal of clinical endocrinology and metabolism (2024)
Elevated plasma levels of calprotectin are associated with a higher risk of developing T2D in the general population and may represent a moveable inflammatory biomarker. This association, however, does not represent a direct effect, and seems dependent on hyperlipidemia and systemic inflammation.