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NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons.

Nicole HamagamiDennis Y WuAdam W ClemensSabin A NettlesHarrison W Gabel
Published in: bioRxiv : the preprint server for biology (2023)
leads to alterations in H3K36me2, DNA methylation, and gene expression that overlap with models of DNMT3A disorders.
Keyphrases
  • dna methylation
  • gene expression
  • genome wide
  • spinal cord
  • copy number
  • amino acid