Declined Humoral Immunity of Kidney Transplant Recipients to SARS-CoV-2 Vaccines.

Waleed H MahallawiWael A AlharbiSultan A AloufiNadir A IbrahimMuntasir M AbdelrahmanBader A AlhomayeedMoutasem Salih AboonqSaeed Awad M AlqahtaniEmad S RajihAbdulaziz M BakhshJillian K Warejko

Published in: Infection and drug resistance (2023)

KTRs' humoral response after SARS-CoV-2 vaccination is dramatically inhibited and wanes. Antibody levels show a significant decline over time in KTRs with hypertension; receiving triple immunosuppressive therapy or steroid-based or antimetabolite-based regimens; receiving mixed mRNA and viral vector vaccines; and with a transplant of >10 years.

Keyphrases

sars cov
immune response
respiratory syndrome coronavirus
blood pressure
binding protein
mesenchymal stem cells
coronavirus disease
bone marrow
cell therapy
replacement therapy