Association between non-alcoholic fatty liver disease and subclinical hypothyroidism in children with obesity.

Anna Di SessaN Cembalo Sambiase SanseverinoR F De SimoneM M MarrapodiG CirilloG R UmanoS GuarinoA PapparellaEmanuele Miraglia Del Giudice Pierluigi Marzuillo

Published in: Journal of endocrinological investigation (2023)

Children with obesity and NAFLD presented increase risk of SH and vice versa likely due to the adverse effect of duration of obesity, obesity degree, and IR. The TM6SF2 E167K exerts a protective role against SH in children with obesity and NAFLD.

Keyphrases

insulin resistance
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
young adults
adipose tissue
emergency department
skeletal muscle
electronic health record
liver fibrosis