Inducing multiple antibodies to treat squamous cell esophageal carcinoma.

Isamu HoshinoYoshihiro NabeyaNobuhiro TakiguchiHisashi GunjiFumitaka IshigeYosuke IwatateAkiko KuwajimaFumiaki ShiratoriRei OkadaHideaki Shimada

Published in: BMC cancer (2020)

The detection rates of LGALS1, HCA25a, HCC-22-5, and HSP70 were 10% higher in patients with ESCC. Gene overexpression may be involved in such antibody production. These four antibodies were applied as a panel in comparison with conventional tumor markers. Moreover, it was confirmed that the combination of this panel and the conventional tumor markers significantly improved the positive rate.

Keyphrases

squamous cell
cell proliferation
heat stress
heat shock
oxidative stress
loop mediated isothermal amplification
label free
genome wide identification
real time pcr
quantum dots