An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes.

Vincent J Vezza Adrian Butterworth Perrine LasserreEwen O BlairAlexander R Macdonald Stuart HannahChristopher RinaldiPaul A Hoskisson Andrew C Ward Alistair LongmuirSteven SetfordEoghan C W FarmerMichael E MurphyDamion K Corrigan

Published in: Chemical communications (Cambridge, England) (2021)

Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.

Keyphrases

sars cov
low cost
loop mediated isothermal amplification
respiratory syndrome coronavirus
label free
gold nanoparticles
sensitive detection
blood glucose
angiotensin ii
high resolution
metabolic syndrome
blood pressure
molecularly imprinted
insulin resistance
real time pcr
electron transfer