Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis.
Daniel Peña-OyarzúnTania FloresVicente A TorresAndrew Frederick Geoffery QuestLorena Lobos-GonzálezCatalina KretschmarPamela OrellanaAndrea Maturana-RamirezAlfredo CriolloMontserrat ReyesPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
The inhibition of Wnt ligand secretion with C59 represents a feasible treatment to prevent the progression of early oral lesions towards OSCC.