Impact of adiposity on risk of female gout among those genetically predisposed: sex-specific prospective cohort study findings over >32 years.

Natalie McCormick Chio YokoseNa LuAmit D JoshiGary C CurhanHyon K Choi

Published in: Annals of the rheumatic diseases (2021)

While excess adiposity and genetic predisposition both are strongly associated with a higher risk of gout, the excess risk of both combined was higher than the sum of each, particularly among women.

Keyphrases

uric acid
insulin resistance
polycystic ovary syndrome
weight gain
metabolic syndrome
genome wide
pregnancy outcomes
copy number
gene expression
skeletal muscle
pregnant women
cervical cancer screening