Essential role of Notch/Hes1 signaling in postnatal pancreatic exocrine development.

Katsutoshi KuriyamaYuzo KodamaMasahiro ShiokawaYoshihiro NishikawaSaiko MaruiTakeshi KuwadaYuko SogabeNobuyuki KakiuchiTeruko TomonoTomoaki MatsumoriAtsushi MimaToshihiro MoritaTatsuki UedaMotoyuki TsudaYuki YamauchiYojiro SakumaYuji OtaTakahisa MarunoNorimitsu UzaRyoichiro KageyamaTsutomu ChibaHiroshi Seno

Published in: Journal of gastroenterology (2021)

Notch signaling has an essential role in pancreatic progenitor cells for the postnatal maturation of exocrine tissue, partly through the formation of centroacinar cells.

Keyphrases

preterm infants
induced apoptosis
cell cycle arrest
cell proliferation
endoplasmic reticulum stress
oxidative stress
signaling pathway
cell death