Confocal Raman Spectroscopy as a tool to measure the prevention of skin penetration by a specifically designed topical medical device.
Sabrina LaingStephan BielfeldtKlaus-Peter WilhelmJoachim ObstPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2019)
Within the precision range of the test method, the investigated product did not penetrate into the compact part of the stratum corneum. The study revealed Raman spectroscopy to be suitable to detect not only penetration but also non-penetration of substances into human skin.