Effects of Voriconazole on the Pharmacokinetics of Vonoprazan in Rats.

Jiquan ShenBo WangShuanghu WangFeifei ChenDeru MengHui JiangYunfang ZhouPeiwu GengQuan ZhouBin Liu

Published in: Drug design, development and therapy (2020)

Our findings provide the evidence of drug-drug interactions between voriconazole and vonoprazan that could occur with pre-administration of voriconazole. Thus, clinicians should pay attention to the resulting changes in pharmacokinetic parameters and accordingly, adjust the dose of vonoprazan in clinical settings.

Keyphrases

helicobacter pylori
endoscopic submucosal dissection
gastroesophageal reflux disease
working memory
palliative care
adverse drug
drug induced
emergency department