Effect of Cumulative Dexamethasone Dose during Concomitant Chemoradiation on Lymphopenia in Patients with Newly Diagnosed Glioblastoma.

Changik Lee Stephen AhnJae Sung ParkJin Ho SongYong Kil HongSin Soo Jeun

Published in: Brain tumor research and treatment (2020)

Female sex, median daily dexamethasone dose ≥2 mg after initiation of CCRT until 4 weeks after completion of CCRT may be associated with acute lymphopenia. However, dexamethasone use itself did not affect OS in patients newly diagnosed with GBM. These results should be validated by further prospective studies controlling for other confounding factors.

Keyphrases

newly diagnosed
low dose
high dose
liver failure
ejection fraction
respiratory failure
patient reported outcomes
gestational age
extracorporeal membrane oxygenation
case control
acute respiratory distress syndrome