Adaptive Modelling of Mutated FMO3 Enzyme Could Unveil Unexplored Scenarios Linking Variant Haplotypes to TMAU Phenotypes.

Simona AlibrandiFabiana NicitaLuigi Donato Concetta ScimoneCarmela RinaldiRosalia D'AngeloAntonina Sidoti

Published in: Molecules (Basel, Switzerland) (2021)

Even if further functional assays will confirm our predictive results, considering the possible role of FMO3 variants with still uncertain effects, might be a relevant step towards the detection of novel scenarios in TMAU etiopathogenesis.

Keyphrases

climate change
copy number
high throughput
loop mediated isothermal amplification
wild type