Humoral and cellular immune responses to the SARS-CoV-2 BNT162b2 vaccine among a cohort of solid organ transplant recipients and healthy controls.

Ahmad H YanisZaid HaddadinAndrew J SpiekerDanya WaqfiDanielle A RankinRana TaljLora ThomasKelly A BirdwellLauren EzzellMarcia BlairJoan EasonRebekkah VarjabedianChristian M WarrenCynthia H NochowiczEric C OlsonJoshua D SimmonsSandra YoderMadeline GuyIsaac ThomsenJames D ChappellSpyros A KalamsNatasha B Halasa

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2021)

Humoral and cellular immune responses to the BNT162b2 vaccine are markedly reduced in SOT recipients as compared to HCs, suggesting that SOT recipients may benefit from more tailored regimens such as higher dose and/or additional vaccinations.

Keyphrases

immune response
sars cov
dendritic cells
kidney transplantation
toll like receptor
respiratory syndrome coronavirus
smoking cessation
coronavirus disease
inflammatory response