The complement system: a novel therapeutic target for Age-related macular degeneration.
Aumer ShughouryDuriye D SevgiThomas A CiullaPublished in: Expert opinion on pharmacotherapy (2023)
Targeting the complement system is a promising therapeutic approach for slowing the rate of GA progression in AMD, potentially improving visual outcomes. However, increased risk of exudative conversion must be considered, and further research is required to identify clinical criteria and best practices for initiating complement inhibitor therapy for GA.