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Skin and lung fibrosis induced by bleomycin in mice: a systematic review.

S GülleA ÇelikM BirlikO Yılmaz
Published in: Reumatismo (2024)
In animal studies, it is important to simultaneously evaluate lung tissues in addition to skin fibrosis induced in mice by subcutaneous BLM application, following the 3R (replacement, reduction, and refinement) principle to avoid cruelty to animals.
Keyphrases
  • high fat diet induced
  • soft tissue
  • wound healing
  • gene expression
  • high glucose
  • diabetic rats
  • insulin resistance
  • liver fibrosis
  • wild type
  • drug induced
  • case control
  • endothelial cells