Cyclization of Bisphosphines to Phosphacycles via the Cleavage of Two Carbon-Phosphorus Bonds by Nickel Catalysis.
Hayato FujimotoMomoka KusanoTakuya KodamaMamoru TobisuPublished in: Organic letters (2019)
The nickel-catalyzed cyclization of bisphosphine derivatives to form various phosphacycles is reported. The reaction proceeds via the cleavage of two carbon-phosphorus bonds of the bisphosphine. Unlike the previously reported palladium catalysts, the use of nickel as a catalyst allows for the cyclization that requires C(alkyl)-P bond cleavage. A phospha-nickelacycle intermediate was successfully isolated and characterized by X-ray crystallography.
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