Improvement of m/z accuracy for linear matrix-assisted laser desorption/ionization time-of-flight mass spectrometer.

Jiajun YuAlexey ChudinovLei LiJinzhao LiuWei GaoZhengxu HuangZhen ZhouSergey NikiforovViatcheslav I Kozlovskiy

Published in: Rapid communications in mass spectrometry : RCM (2020)

It is expected that the proposed method will significantly increase the dynamic range, since it becomes possible to sum up corrected individual mass spectra without a significant loss of resolution. Timescale adjusting can be used for both linear TOF instruments and reflector systems of various configurations.

Keyphrases

mass spectrometry
high resolution
ms ms
single molecule
density functional theory
patient reported outcomes