Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.

Kai ChenYaohui YuYishu WangYi ZhuChaoren QinJintao XuXiangjie ZouTianqi TaoYang LiYiqiu Jiang

Published in: Drug design, development and therapy (2024)

This study elucidates how AM regulates chondrocyte ferroptosis, impacting OA progression, providing a theoretical basis and experimental support for AM's scientific application.

Keyphrases

cell death
knee osteoarthritis
rheumatoid arthritis
gene expression
dna methylation