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Temporal changes in macrophage phenotype after peripheral nerve injury.

Joy E TomlinsonEmilija ŽygelytėJennifer K GrenierMichael G EdwardsJonathan Cheetham
Published in: Journal of neuroinflammation (2018)
Overall, this study provides a framework to evaluate the phenotype of macrophages over time, and provides a broader and more precise assessment of gene expression changes than has previously been commonly used. This data suggests ways in which polarization may be modulated to improve repair.
Keyphrases
  • peripheral nerve
  • gene expression
  • dna methylation
  • adipose tissue
  • deep learning
  • data analysis
  • clinical evaluation