Temporal changes in macrophage phenotype after peripheral nerve injury.
Joy E TomlinsonEmilija ŽygelytėJennifer K GrenierMichael G EdwardsJonathan CheethamPublished in: Journal of neuroinflammation (2018)
Overall, this study provides a framework to evaluate the phenotype of macrophages over time, and provides a broader and more precise assessment of gene expression changes than has previously been commonly used. This data suggests ways in which polarization may be modulated to improve repair.