A method to investigate muscle target-specific transcriptional signatures of single motor neurons.
Bianka BerkiFabio SacherAntoine FagesPatrick TschoppMaëva LuxeyPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2022)
Our method provides a unique approach to study muscle target-specific motor neuron transcriptomes at a single-cell resolution. We anticipate that our method will provide key insights into the transcriptional logic underlying motor neuron pool specialization and proper neuromuscular circuit assembly and refinement.