Gastric-type gene expression and phenotype in non-terminal respiratory unit type adenocarcinoma of the lung with invasive mucinous adenocarcinoma morphology.

Myoung Ju KohDong Hoon ShinSo-Jeong LeeChung-Su HwangHyun Jung LeeAhrong KimWon Young ParkJung Hee LeeKyung Un ChoiJee Yeon KimChang Hun LeeMee Young Sol

Published in: Histopathology (2021)

Our results showed the level of genes expressed in stomach mucosa was increased in IMA compared to TRU type adenocarcinoma, supporting gastric differentiation of IMA. This finding may help the understanding of the pathogenesis of IMA and discovery of therapeutic targets.

Keyphrases

gene expression
squamous cell carcinoma
locally advanced
small molecule
high throughput
radiation therapy
rectal cancer
single cell