Hydrophilic biomaterial intravenous hydrogel catheter for complication reduction in PICC and midline catheters.
Nancy L MoureauPublished in: Expert review of medical devices (2024)
Patients commonly require PICC or midline catheters for treatment to establish a reliable form of intravenous access. Catheters, while reliable in most cases, are not without complications, including occlusion, thrombosis and infection, each related to cellular adherence to the catheter material. Hydrophilic catheter coatings and composites have been developed to mitigate these thrombotic complications, reduce adherence of blood and bacterial cells to catheters and provide greater patient safety with these devices. Hydrogel materials are highly biocompatible and have been effective in reducing cellular adherence and the formation of biofilms on surfaces. Smooth hydrophilic catheter surfaces are potentially more comfortable for the patient, with reduced friction during insertion and removal. A catheter constructed of hydrophilic biomaterial, a hydrogel composite material, may minimize thrombotic complications in PICC and midline catheters, improving catheter performance and outcomes for patients.
Keyphrases
- patient safety
- end stage renal disease
- ultrasound guided
- chronic kidney disease
- ejection fraction
- newly diagnosed
- drug delivery
- liquid chromatography
- high dose
- risk factors
- escherichia coli
- tissue engineering
- type diabetes
- pulmonary embolism
- peritoneal dialysis
- hyaluronic acid
- patient reported outcomes
- staphylococcus aureus
- biofilm formation
- cystic fibrosis
- cell death
- adipose tissue
- high resolution
- candida albicans
- glycemic control
- solid phase extraction
- signaling pathway
- endoplasmic reticulum stress