Contribution of acute infarcts to cerebral small vessel disease progression.
Annemieke Ter TelgteKim WiegertjesBenno GesierichJosé P MarquesMathias HuebnerJabke J de KlerkFloris H B M SchreuderMiguel A Araque CaballeroHugo J KuijfDavid G NorrisCatharina J M KlijnMartin DichgansAnil M TuladharMarco DueringFrank-Erik de LeeuwPublished in: Annals of neurology (2019)
DWI+ lesions explain only a small proportion of the total WMH progression. Hence, WMH progression seems to be mostly driven by factors other than acute infarcts. DWI+ lesions explain the majority of incident lacunes and small cavities, and almost one-third of incident microbleeds, confirming that WMH, lacunes, and microbleeds, although heterogeneous on MRI, can have a common initial appearance on MRI. ANN NEUROL 2019;86:582-592.