Login / Signup

Therapeutic potential of conditioned medium obtained from deferoxamine preconditioned umbilical cord mesenchymal stem cells on diabetic nephropathy model.

Serbay OzkanBasak IsildarMerve ErcinSelda Gezginci-OktayogluDildar KonukogluNeşet NeşetoğluMahmut OnculMeral Koyutürk
Published in: Stem cell research & therapy (2022)
DFS-CM can be more effective in the treatment of DN by reducing podocyte damage and tubular apoptotic cell death and regulating autophagic activity with its more concentrated secretome content than N-CM.
Keyphrases
  • cell death
  • umbilical cord
  • diabetic nephropathy
  • mesenchymal stem cells
  • cell cycle arrest
  • bone marrow
  • cell therapy
  • oxidative stress
  • high glucose
  • stem cells
  • combination therapy
  • endothelial cells