Association of topiramate prescribed for any indication with reduced alcohol consumption in electronic health record data.

Henry R KranzlerShirley H LeongMichelle NapsEmily E Hartwell David A Fiellin Christopher T Rentsch

Published in: Addiction (Abingdon, England) (2022)

Among individuals with no history of alcohol use disorder, topiramate appears to be associated with reduced drinking. This small effect is most evident among patients with higher baseline drinking levels and at a higher average daily topiramate dosage.

Keyphrases

alcohol consumption
electronic health record
alcohol use disorder
clinical decision support
adverse drug
physical activity
big data