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Observed evidence for guideline-recommended genes in predicting prostate cancer risk from a large population-based cohort.

Jun WeiWancai YangZhuqing ShiLucy LuQiang WangW Kyle ResurreccionValentina EngelmannS Lilly ZhengPeter J HulickKathleen A CooneyWilliam B IsaacsBrian T HelfandJim LuJianfeng Xu
Published in: The Prostate (2021)
Observed evidence for PCa risk was found for four of the 10 guideline-recommended genes in this large population-based study. Mutations in these four genes can be interpreted with confidence in genetic counseling for PCa risk assessment. Evidence for the remaining six genes needs to be further evaluated in larger studies.
Keyphrases
  • genome wide
  • prostate cancer
  • risk assessment
  • bioinformatics analysis
  • genome wide identification
  • dna methylation
  • radical prostatectomy
  • heavy metals
  • human health
  • hiv testing
  • case control
  • antiretroviral therapy