Infectiousness of HIV-Seropositive Patients with Tuberculosis in a High-Burden African Setting.
Leonardo MartinezJuliet N SekandiMaría E CastellanosSarah ZalwangoChristopher C WhalenPublished in: American journal of respiratory and critical care medicine (2017)
This study suggests that HIV-seropositive tuberculosis cases may be less infectious than HIV-seronegative patients only when they are smear-negative or lack cavitary lung disease. These results may explain heterogeneity between prior studies and provide evidence suggesting that tuberculosis contact investigation should include HIV-seropositive index cases in high disease burden settings.
Keyphrases
- hiv aids
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- men who have sex with men
- mycobacterium tuberculosis
- pulmonary tuberculosis
- end stage renal disease
- south africa
- chronic kidney disease
- ejection fraction
- peritoneal dialysis
- emergency department
- single cell
- adverse drug
- patient reported outcomes
- electronic health record