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Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling.

Reyes Gamez-BelmonteMousumi MahapatroLena ErkertMiguel Gonzalez-AceraElisabeth NaschbergerYuqiang YuMireia Tena-GaritaonaindiaJay V PatankarYara WagnerEva PodstawaLena SchödelMarvin BubeckMarkus Friedrich NeurathMichael StürzlChristoph Becker
Published in: Gut (2022)
pathway. PSEN1 inhibition could be a useful strategy in treatment of CRC.
Keyphrases
  • small cell lung cancer
  • early onset
  • epidermal growth factor receptor
  • tyrosine kinase
  • combination therapy
  • replacement therapy
  • smoking cessation