Hydroxychloroquine in Lupus Pregnancy and Risk of Preeclampsia.

Amadeia RectorIvana MarićYashaar ChaichianEliza ChakravartyMiranda CantuMichael H WeismanGary M ShawMaurice L DruzinJulia F Simard

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2024)

Using a large insurance-based database, we did not observe a decreased risk of preeclampsia associated with HCQ treatment in pregnancy, although we cannot rule out residual and unmeasured confounding and misclassification. Further studies leveraging large population-based data and prospective collection could characterize how HCQ influences preeclampsia risk in pregnant patients with SLE and among persons at greater risk of hypertensive disorders of pregnancy.

Keyphrases

pregnancy outcomes
early onset
pregnant women
systemic lupus erythematosus
preterm birth
blood pressure
emergency department
big data
artificial intelligence