Effects of Neuroanatomic Structural Distances on Pituitary Function After Stereotactic Radiosurgery: A Multicenter Study.
Natasha IronsideChing-Jen ChenZhiyuan XuDavid SchlesingerMary Lee VanceGregory K HongJohn A JaneSamir PatelShray K BindalAjay NiranjanL Dade LunsfordRoman LiscakThomas ChytkaJana JezkovaOmran SaifiDaniel M TrifilettiAssaf BergerJuan AlzateKenneth BernsteinDouglas KondziolkaHerwin SpeckterWenceslao HernandezErwin LazoSelcuk PekerYavuz SamanciBrad E ZachariaChristine MauRodney E WegnerMatthew J ShepardDavid MathieuMichel MailletJason P SheehanPublished in: Neurosurgery (2023)
Achieving a distance between the center of the pituitary stalk and the tumor margin isodose ≥3.95 mm predicted anterior pituitary function preservation. For smaller treatment volumes <2.34 mL, the optimal distance was ≥2.95 mm. This may be modifiable during trans-sphenoidal resection to preserve pituitary function.
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