Pneumococcal meningitis in adults: a prospective nationwide cohort studY over a 20-year period.
Diederik L H KoelmanMatthijs C BrouwerLiora Ter HorstMerijn W BijlsmaArie van der EndeDiederik van de BeekPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Implementation of conjugate vaccines and adjunctive dexamethasone therapy have changed the incidence and outcome of pneumococcal meningitis in adults over the last two decades. Despite recent advances pneumococcal meningitis remains associated with a residual high rate of mortality and morbidity.