SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation.

Jing LiuWeiwei BaiTianxing ZhouYongjie XieBo YangJingyan SunYifei WangXueyang LiXupeng HouZiyun LiuDanqi FuJingrui YanWenna JiangKaili ZhaoBodong ZhouShuai YuanYu GuoHongwei WangAntao ChangSong GaoLei ShiChongbiao HuangShengyu YangBaocun Sun

Published in: Gut (2023)

SDCBP promotes the proliferation and metastasis of PDAC by preventing YAP1 from β-TrCP-mediated proteasomal degradation. Therefore, ZnPT could be a promising therapeutic strategy to inhibit PDAC progression by suppressing SDCBP.

Keyphrases

signaling pathway