Structural and functional connectivity in children and adolescents with and without attention deficit/hyperactivity disorder.
Dienke J BosBob OranjeMichelle AchterbergChantal VlaskampSara AmbrosinoMarcel A de ReusMartijn P van den HeuvelSerge A R B RomboutsSarah DurstonPublished in: Journal of child psychology and psychiatry, and allied disciplines (2017)
Resting-state networks show a more diffuse pattern of connectivity in children with ADHD. The increases in functional connectivity in right IFG and bilateral mPFC in children with ADHD may reflect reduced or delayed functional segregation of prefrontal brain regions. As these functional changes were not accompanied by changes in WM, they may precede the development of the frequently reported changes in WM structure.