Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models.

Vikash Kansal Andre J BurnhamBrendan L C KinneyNabil F SabaChrystal PaulosGregory B LesinskiZachary S BuchwaldNicole C Schmitt

Published in: Journal for immunotherapy of cancer (2023)

These results suggest that statins deserve further study as well-tolerated, inexpensive drugs that may enhance responses to PD-1 checkpoint blockade and other immunotherapies for HNSCC.

Keyphrases

cardiovascular disease
dna damage
cell cycle
type diabetes
oxidative stress