Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment.
Xiangyang ZhangBin QinMin WangJunyi FengChenglin ZhangChengshen ZhuSuqin HeHao LiuYaohe WangSaadyah E AverickNga T N VoLei HuangWentao LiuZhimin WangPublished in: International journal of nanomedicine (2022)
We successfully prepared a novel siRNA delivery system with the double capability of tumor targeting and pH response, which can break through the biological barriers to penetrate deep into tumors and achieve better therapeutic tumor effects, providing a new ideal delivery platform for siRNA.