Different mechanisms guide the antinociceptive effect of bone marrow-mononuclear cells and bone marrow-mesenchymal stem/stromal cells in trigeminal neuralgia.
Catarina Milena Mota CostaDourivaldo Silva SantosLuiza Carolina França OpretzkaGessica Sabrina de Assis SilvaGirlaine Café SantosAfrânio Ferreira EvangelistaMilena Botelho Pereira SoaresCristiane Flora VillarrealPublished in: Life sciences (2024)
Importantly, these data suggest an IL-10-induced disease-modifying profile related to MSC treatment and reinforce cell therapy's potential in treating trigeminal neuralgia.
Keyphrases
- bone marrow
- cell therapy
- mesenchymal stem cells
- induced apoptosis
- stem cells
- neuropathic pain
- cell cycle arrest
- high glucose
- diabetic rats
- electronic health record
- peripheral blood
- oxidative stress
- spinal cord injury
- endoplasmic reticulum stress
- cell death
- machine learning
- cell proliferation
- spinal cord
- deep learning