Applications of single-cell sequencing for the field of otolaryngology: A contemporary review.
Madeline P PyleMichael HoaPublished in: Laryngoscope investigative otolaryngology (2020)
Although there are limitations to the translation of scRNA-Seq to the clinic, we show that its use in otolaryngology can give physicians insight into the tissue heterogeneity within their patient's diseased tissue giving them information on disease pathogenesis, novel disease biomarkers or druggable targets, and aid in selecting patient-specific drug cocktails.