Initial results of a first-in-human study on the PlasmaWire™ System, a new radiofrequency wire for recanalization of chronic total occlusions.
Daitaro KannoEtsuo TsuchikaneKenya NasuOsamu KatohYoshifumi KashimaUmihiko KanekoTsutomu FujitaYoriyasu SuzukiTakahiko SuzukiPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2017)
The PlasmaWireTM System was shown to be safe and effective in obtaining CTO recanalization through a re-entry channel utilizing plasma-mediated ablation while reducing procedure time. The PlasmaWire™ System is a new bi-polar RF wire system utilizing plasma-mediated ablation for channel creation to facilitate CTO recanalization. This first-in-human study in which seven patients were enrolled was conducted to demonstrate the safety, efficacy, and efficiency of this system for CTO recanalization. Channels through the CTOs were successfully created within a few seconds by applying RF energy between the tips of two independent PlasmaWireTM wires and recanalization was achieved in all cases without any complication. The PlasmaWireTM System may safely facilitate CTO recanalization with less vessel injury and improve initial results of CTO PCI while reducing procedure time.
Keyphrases
- middle cerebral artery
- endovascular treatment
- endothelial cells
- newly diagnosed
- acute myocardial infarction
- coronary artery disease
- ejection fraction
- acute coronary syndrome
- percutaneous coronary intervention
- prognostic factors
- chronic kidney disease
- patient reported outcomes
- st segment elevation myocardial infarction
- left ventricular
- st elevation myocardial infarction
- ultrasound guided
- atrial fibrillation
- antiplatelet therapy