PET imaging of Aspergillus infection using Zirconium-89 labeled anti-β-glucan antibody fragments.

Jianhao LaiSwati ShahNeysha Martinez-OrengoRekeya KnightEyob AlemuMitchell L TurnerBenjamin WangAnna LyndakerJianfeng ShiFalguni BasuliDima A Hammoud

Published in: European journal of nuclear medicine and molecular imaging (2024)

Zr]Zr-DFO-HA-βG-Fab can be used to detect fungal infections in vivo. Targeting distinct components of the fungal cell wall is a viable approach to developing fungal-specific PET tracers.

Keyphrases

pet imaging
cell wall
positron emission tomography
computed tomography
cancer therapy
drug delivery
pet ct