Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease.

Prasenjit DasSudha BattuLalita MehraAlka SinghMuzaffar AhmadAshish AgarwalAshish ChauhanAnam AhmadSreenivas VishnubhatlaSiddhartha Datta GuptaVineet AhujaGovind Makharia

Published in: Indian journal of pathology & microbiology (2024)

Our data suggests that ISC niche failure is a plausible hypothesis for villous flattening in patients with CeD, resulting from pericrypt IgA anti-TG2 antibody complex-mediated stromal depletion.

Keyphrases

small bowel
celiac disease
stem cells
bone marrow
electronic health record
big data
mesenchymal stem cells
combination therapy
replacement therapy
deep learning
data analysis
artificial intelligence