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Visible light-mediated halogenation of organic compounds.

Alexey A FestaOlga A StorozhenkoLeonid G VoskressenskyErik V Van der Eycken
Published in: Chemical Society reviews (2023)
The use of visible light and photoredox catalysis emerged as a powerful and sustainable tool for organic synthesis, showing high value for distinctly different ways of bond creation. Halogenated compounds are the cornerstone of contemporary organic synthesis: it is almost impossible to develop a route towards a pharmaceutical reagent, agrochemical, natural product, etc. without the involvement of halogen-containing intermediates. Moreover, the halogenated derivatives as final products became indispensable for drug discovery and materials science. The idea of this review is to understand and summarise the impact of visible light-promoted chemistry on halogenation and halofunctionalisation reactions.
Keyphrases
  • visible light
  • drug discovery
  • water soluble
  • public health