Assessing graph-based read mappers against a baseline approach highlights strengths and weaknesses of current methods.

Ivar GryttenKnut D RandAlexander J NederbragtGeir K Sandve

Published in: BMC genomics (2020)

Our method is implemented in a tool Two-step Graph Mapper, which is available at https://github.com/uio-bmi/two_step_graph_mapperalong with data and scripts for reproducing the experiments. Our method highlights characteristics of the current generation of graph-based read mappers and shows potential for improvement for future graph-based read mappers.

Keyphrases

convolutional neural network
neural network
single molecule
body mass index
deep learning
big data
electronic health record
artificial intelligence
data analysis