Prognostic validation of a new classification system for extent of resection in glioblastoma: a report of the RANO resect group.
Philipp KarschniaJacob S YoungAntonio DonoLevin HäniTommaso SciortinoFrancesco BrunoStephanie T JuengerNico TeskeRamin A MorshedAlexander F HaddadYalan ZhangSophia StoeckleinMichael WellerMichael A VogelbaumJuergen BeckNitin TandonShawn Hervey-JumperAnnette M MolinaroRoberta RudàLorenzo BelloOliver SchnellYoshua EsquenaziMaximilian I RugeStefan J GrauMitchell S BergerSusan M ChangMartin van den BentJoerg-Christian TonnPublished in: Neuro-oncology (2022)
The proposed "RANO categories for extent of resection in glioblastoma" are highly prognostic and may serve for stratification within clinical trials. Removal of non-CE tumor beyond the CE tumor borders may translate into additional survival benefit, providing a rationale to explicitly denominate such 'supramaximal CE resection'.
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