LMS-based continuous pediatric reference values for soluble receptor activator of nuclear factor kappa B ligand (sRANKL) and osteoprotegerin (OPG) in the HARP cohort.
Helene TietzeVeronika PottNele KanzelmeyerNima MemaranUlrich BaumannCharlotte MindermannAdriana SuhlrieJens DrubeAnette MelkAnibh M DasDirk SchnabelDieter HaffnerMaren Leifheit-NestlerPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2023)
This is the first report of LMS-based continuous pediatric reference percentiles for sRANKL, OPG and sRANKL/OPG ratio that allows calculation of standardized patient z-scores to assess bone metabolic turnover in children.