SNP genotype calling and quality control for multi-batch-based studies.
Sujin SeoKyungtaek ParkJang Jae LeeKyu Yeong ChoiKun Ho LeeSungho WonPublished in: Genes & genomics (2019)
We proposed a new strategy that detects batch effects with probe intensity measurement and calls genotypes in the presence of batch effects. The application of the proposed method to real data shows that it produces a balanced approach. Furthermore, the proposed method can be extended to various scenarios with a simple modification.