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Modification of Lugano criteria by pre-infusion tumor kinetics improves early survival prediction for patients with lymphoma under chimeric antigen receptor T-cell therapy.

Michael WinkelmannViktoria BlumenbergMarion SubkleweChristina QuellVeit BückleinMaria IngenerfMarcus UnterrainerChristian SchmidtFranziska J DekorsyPeter BartensteinJens RickeMichael von Bergwelt-BaildonMarion SubkleweWolfgang Gerhard Kunz
Published in: Journal for immunotherapy of cancer (2023)
determined at 30-day FU1 showed better OS prognostication for patients with overall PD according to Lugano criteria. Therefore, this modification of the Lugano classification should be explored as a potential novel imaging biomarker of early response and should be validated prospectively in future studies.
Keyphrases
  • cell therapy
  • stem cells
  • high resolution
  • machine learning
  • deep learning
  • mesenchymal stem cells
  • low dose
  • diffuse large b cell lymphoma
  • risk assessment
  • climate change
  • photodynamic therapy