Associations of risk factor burden and genetic predisposition with the 10-year risk of atrial fibrillation: observations from a large prospective study of 348,904 participants.
Junguo ZhangGe ChenChongJian WangXiaojie WangZhengmin Min QianMiao CaiMichael G VaughnElizabeth BingheimHaitao LiYanhui GaoGregory Y H LipHualiang LinPublished in: BMC medicine (2023)
Risk factor burden together with a genetic predisposition is associated with the 10-year risk of AF. Our results may be helpful in selecting high-risk individuals for primary prevention of AF and facilitating subsequent health interventions.
Keyphrases
- atrial fibrillation
- risk factors
- genome wide
- oral anticoagulants
- left atrial
- catheter ablation
- healthcare
- left atrial appendage
- direct oral anticoagulants
- public health
- heart failure
- copy number
- mental health
- physical activity
- percutaneous coronary intervention
- dna methylation
- coronary artery disease
- health promotion
- venous thromboembolism
- human health